Studies on the larvicidal properties of extracts and fractions from Kotschya uguenensis Verdc. were done by long-term exposure of Anopheles gambiae s.s. larvae.The cumulative mean percentage mortalities and deformities at different concentrations for the extracts and fractions were recorded after every 24 h. Treatment of A. gambiae s.s. larvae with K. uguenensis extracts showed growth disruption by forming elongated guts and resulting in eventual death.